People
Ying Xiao

Ying Xiao

Graduate Student in Chemistry
(November 2008-December 2013)

B.S. Chemistry, Wuhan University, 2008
Ph.D. Chemistry, University of Illinois at Urbana-Champaign, 2013

 

Current position: Scientist II, GENEWIZ, South Plainfield, NJ

Email: konyriolina@gmail.com

   

Brief Biography

Ying Xiao received her B.S. degree in chemistry from Wuhan University, China in 2008. Starting in Fall 2008, she was a graduate student in chemistry at the University of Illinois at Urbana-Champaign, working under the supervision of Prof. Scott K. Silverman on the in vitro selection of deoxyribozymes. She earned her Ph.D. degree in December 2013.

Research Interests

In my research in the Silverman lab, I developed deoxyribozymes for sequence-specific and site-specific cleavage of DNA. I also studied these deoxyribozymes biochemically.

  • "DNA Catalysis of a Normally Disfavored RNA Hydrolysis Reaction", D. J. Parker, Y. Xiao, J. M. Aguilar, and S. K. Silverman, J. Am. Chem. Soc. 2013, 135, 8472-8475. [pdf] [Supp Info] [PubMed entry]

  • "Systematic Evaluation of the Dependence of Deoxyribozyme Catalysis on Random Region Length", T. E. Velez, J. Singh, Y. Xiao, E. C. Allen, O. Y. Wong, M. Chandra, S. C. Kwon, and S. K. Silverman, ACS Comb. Sci. 2012, 14, 680-687. [pdf] [Supp Info] [PubMed entry]

  • "Establishing Broad Generality of DNA Catalysts for Site-Specific Hydrolysis of Single-Stranded DNA", Y. Xiao, R. J. Wehrmann, N. A. Ibrahim, and S. K. Silverman, Nucleic Acids Res. 2012, 40, 1778-1786. [pdf] [Supp Info] [PubMed entry]

  • "Merely Two Mutations Switch a DNA-Hydrolyzing Deoxyribozyme from Heterobimetallic (Zn2+/Mn2+) to Monometallic (Zn2+-only) Behavior", Y. Xiao, E. C. Allen, and S. K. Silverman, Chem. Commun. 2011, 47, 1749-1751. [pdf] [Supp Info] [PubMed entry]

  • "Functional Compromises Among pH Tolerance, Site Specificity, and Sequence Tolerance for a DNA-Hydrolyzing Deoxyribozyme", Y. Xiao, M. Chandra, and S. K. Silverman, Biochemistry 2010, 49, 9630-9637. [pdf] [Supp Info] [PubMed entry]